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Introduction to Systems Biology

This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions.

Course Summary

Why to enroll this course?

As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems.

These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability.

In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials.

What are the properties of such subcellular and cellular systems?

Examples will be discussed to demonstrate “how” cell- level functions arise and “why” mechanistic knowledge allows us to predict cellular behaviors leading to disease states and drug responses.

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